Ontology highlight
ABSTRACT:
SUBMITTER: Henrion M
PROVIDER: S-EPMC3554205 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Henrion Marc M Frampton Matthew M Scelo Ghislaine G Purdue Mark M Ye Yuanqing Y Broderick Peter P Ritchie Alastair A Kaplan Richard R Meade Angela A McKay James J Johansson Mattias M Lathrop Mark M Larkin James J Rothman Nathaniel N Wang Zhaoming Z Chow Wong-Ho WH Stevens Victoria L VL Ryan Diver W W Gapstur Susan M SM Albanes Demetrius D Virtamo Jarmo J Wu Xifeng X Brennan Paul P Chanock Stephen S Eisen Timothy T Houlston Richard S RS
Human molecular genetics 20121125 4
Genome-wide association studies (GWASs) of renal cell cancer (RCC) have identified four susceptibility loci thus far. To identify an additional RCC common susceptibility locus, we conducted a GWAS and performed a meta-analysis with published GWASs (totalling 2215 cases and 8566 controls of European background) and followed up the most significant association signals [nine single nucleotide polymorphisms (SNPs) in eight genomic regions] in 3739 cases and 8786 controls. A combined analysis identif ...[more]