Ontology highlight
ABSTRACT:
SUBMITTER: Voorberg-van der Wel A
PROVIDER: S-EPMC3554669 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PloS one 20130124 1
A major challenge for strategies to combat the human malaria parasite Plasmodium vivax is the presence of hypnozoites in the liver. These dormant forms can cause renewed clinical disease after reactivation through unknown mechanisms. The closely related non-human primate malaria P. cynomolgi is a frequently used model for studying hypnozoite-induced relapses. Here we report the generation of the first transgenic P. cynomolgi parasites that stably express fluorescent markers in liver stages by tr ...[more]