Ontology highlight
ABSTRACT:
SUBMITTER: Voorberg-van der Wel AM
PROVIDER: S-EPMC6941962 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Communications biology 20200103
<i>Plasmodium vivax</i> malaria is characterized by repeated episodes of blood stage infection (relapses) resulting from activation of dormant stages in the liver, so-called hypnozoites. Transition of hypnozoites into developing schizonts has never been observed. A barrier for studying this has been the lack of a system in which to monitor growth of liver stages. Here, exploiting the unique strengths of the simian hypnozoite model <i>P. cynomolgi</i>, we have developed green-fluorescent (GFP) hy ...[more]