Ontology highlight
ABSTRACT:
SUBMITTER: Gill VL
PROVIDER: S-EPMC3557806 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Gill Vanessa Leah VL Aich Udayanath U Rao Srinivasa S Pohl Chris C Zaia Joseph J
Analytical chemistry 20130103 2
Heparan sulfate (HS) and chondroitin sulfate/dermatan sulfate (CS/DS) glycosaminoglycans (GAGs) participate in many important biological processes. Quantitative disaccharide analysis of HS and CS/DS is essential for the characterization of GAGs and enables modeling of the GAG domain structure. Methods involving enzymatic digestion and chemical depolymerization have been developed to determine the type and location of sulfation/acetylation modifications as well as uronic acid epimerization. Enzym ...[more]