Ontology highlight
ABSTRACT:
SUBMITTER: Yeh EA
PROVIDER: S-EPMC3560418 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20130118 4
All four diastereomers of a typical saturated oligoisoprenoid, 4,8,12-trimethylnonadecanol, are made by an iterative three-step cycle with the aid of traceless thionocarbonate fluorous tags to encode configurations. The tags have a minimum number of total fluorine atoms, starting at zero and increasing in increments of one. With suitable acquisition and data processing, each diastereomer exhibits characteristic chemical shifts of methyl resonances in its (1)H and (13)C NMR spectra. Together, the ...[more]