Ontology highlight
ABSTRACT:
SUBMITTER: Fulzele K
PROVIDER: S-EPMC3567340 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Fulzele Keertik K Krause Daniela S DS Panaroni Cristina C Saini Vaibhav V Barry Kevin J KJ Liu Xiaolong X Lotinun Sutada S Baron Roland R Bonewald Lynda L Feng Jian Q JQ Chen Min M Weinstein Lee S LS Wu Joy Y JY Kronenberg Henry M HM Scadden David T DT Divieti Pajevic Paola P
Blood 20121116 6
Hematopoietic progenitors are regulated in their respective niches by cells of the bone marrow microenvironment. The bone marrow microenvironment is composed of a variety of cell types, and the relative contribution of each of these cells for hematopoietic lineage maintenance has remained largely unclear. Osteocytes, the most abundant yet least understood cells in bone, are thought to initiate adaptive bone remodeling responses via osteoblasts and osteoclasts. Here we report that these cells reg ...[more]