Ontology highlight
ABSTRACT:
SUBMITTER: Xu L
PROVIDER: S-EPMC3570076 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Xu Limin L Zhou Jianqing J Huang Stephanie S Huang Yi Y LE Yanping Y Jiang Danjie D Wang Feiming F Yang Xi X Xu Weifeng W Huang Xiaoyan X Dong Changzheng C Zhang Lina L Ye Meng M Lian Jiangfang J Duan Shiwei S
Experimental and therapeutic medicine 20130121 3
Previous genome-wide association studies (GWAS) have revealed seven single nucleotide polymorphisms (SNPs) that affect lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) activity or levels in American and European individuals. A total of 290 coronary heart disease (CHD) patients, 198 non-CHD patients and 331 unrelated healthy volunteers were recruited for the present case-control study of Han Chinese. Four SNPs (rs964184 of ZNF259, rs7528419 of CELSR2 and rs7756935 and rs1805017 of PLA2G7) we ...[more]