Ontology highlight
ABSTRACT:
SUBMITTER: He X
PROVIDER: S-EPMC3570461 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
He Xuan X Li Dan D Luo Zhenwu Z Liang Hua H Peng Hong H Zhao Yangyang Y Wang Nidan N Liu Donghua D Qin Chuan C Wei Qiang Q Yan Huimin H Shao Yiming Y
PloS one 20130212 2
Increasing evidence indicates that antibody-dependent cellular cytotoxicity (ADCC) contributes to the control of HIV/SIV infection. However, little is known about the ADCC function of natural killer (NK) cells in non-human primate model. Here we demonstrated that ADCC function of NK cells was significantly compromised in chronic SIV/SHIV infection, correlating closely with the expression of FcγRIIIa receptor (CD16) on NK cells. CD32, another class of IgG Fc receptors, was identified on NK cells ...[more]