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Alkynoate synthesis through the vinylogous reactivity of rhodium(II) carbenoids.

ABSTRACT: Siloxy group migration: A rhodium(II) carbenoid approach has been developed for the synthesis of alkynoates. This transformation combines the addition of enol ethers at the vinylogous position of ?-siloxy-substituted vinyldiazo derivatives with a siloxy group migration to give the products as single diastereomers.

SUBMITTER: Valette D

PROVIDER: S-EPMC3580044 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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Alkynoate synthesis through the vinylogous reactivity of rhodium(II) carbenoids.

Valette Damien D Lian Yajing Y Haydek John P JP Hardcastle Kenneth I KI Davies Huw M L HM

Angewandte Chemie (International ed. in English) 20120716 34

Siloxy group migration: A rhodium(II) carbenoid approach has been developed for the synthesis of alkynoates. This transformation combines the addition of enol ethers at the vinylogous position of β-siloxy-substituted vinyldiazo derivatives with a siloxy group migration to give the products as single diastereomers. ...[more]

PMID: 22807172

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