Ontology highlight
ABSTRACT:
SUBMITTER: Cho YS
PROVIDER: S-EPMC3582398 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Nature genetics 20111211 1
We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes (T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D genome-wide association studies (6,952 cases with T2D and 11,865 controls) with a stage 2 in silico replication analysis (5,843 cases and 4,574 controls) and a stage 3 de novo replication analysis (12,284 cases and 13,172 controls). The combined analysis identified eight new T2D loci reaching genome-wide significance, whi ...[more]