Ontology highlight
ABSTRACT:
SUBMITTER: Richmond D
PROVIDER: S-EPMC3583661 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Richmond Daniel D Rizkallah Raed R Liang Fengshan F Hurt Myra M MM Wang Yanchang Y
Molecular biology of the cell 20130102 5
In all eukaryotic cells, DNA is packaged into multiple chromosomes that are linked to microtubules through a large protein complex called a kinetochore. Previous data show that the kinetochores are clustered together during most of the cell cycle, but the mechanism and the biological significance of kinetochore clustering are unknown. As a kinetochore protein in budding yeast, the role of Slk19 in the stability of the anaphase spindle has been well studied, but its function in chromosome segrega ...[more]