Ontology highlight
ABSTRACT:
SUBMITTER: Anderson BN
PROVIDER: S-EPMC3584232 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Anderson Brett N BN Muthukumar Murugappan M Meller Amit A
ACS nano 20121231 2
Controlling DNA translocation speed is critically important for nanopore sequencing as free electrophoretic threading is far too rapid to resolve individual bases. A number of promising strategies have been explored in recent years, largely driven by the demands of next-generation sequencing. Engineering DNA-nanopore interactions (known to dominate translocation dynamics) with organic coatings is an attractive method as it does not require sample modification, processive enzymes, or complicated ...[more]