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Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype.


ABSTRACT: In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.

SUBMITTER: Izzo G 

PROVIDER: S-EPMC3584260 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype.

Izzo Giselle G   Forlenza Orestes V OV   Santos Bernardo dos Bd   Bertolucci Paulo H F PH   Ojopi Elida B EB   Gattaz Wagner F WF   Kerr Daniel Shikanai DS  

Clinics (Sao Paulo, Brazil) 20130101 2


In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele. ...[more]

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