Ontology highlight
ABSTRACT:
SUBMITTER: Massire C
PROVIDER: S-EPMC3592073 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Massire Christian C Buelow Daelynn R DR Zhang Sean X SX Lovari Robert R Matthews Heather E HE Toleno Donna M DM Ranken Raymond R RR Hall Thomas A TA Metzgar David D Sampath Rangarajan R Blyn Lawrence B LB Ecker David J DJ Gu Zhengming Z Walsh Thomas J TJ Hayden Randall T RT
Journal of clinical microbiology 20130109 3
Invasive fungal infections are a significant cause of morbidity and mortality among immunocompromised patients. Early and accurate identification of these pathogens is central to direct therapy and to improve overall outcome. PCR coupled with electrospray ionization mass spectrometry (PCR/ESI-MS) was evaluated as a novel means for identification of fungal pathogens. Using a database grounded by 60 ATCC reference strains, a total of 394 clinical fungal isolates (264 molds and 130 yeasts) were ana ...[more]