Ontology highlight
ABSTRACT:
SUBMITTER: Bahar MW
PROVIDER: S-EPMC3592137 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Bahar Mohammad W MW Sarin L Peter LP Graham Stephen C SC Pang Jances J Bamford Dennis H DH Stuart David I DI Grimes Jonathan M JM
Journal of virology 20130102 6
Infectious pancreatic necrosis virus (IPNV), a member of the family Birnaviridae, infects young salmon, with a severe impact on the commercial sea farming industry. Of the five mature proteins encoded by the IPNV genome, the multifunctional VP3 has an essential role in morphogenesis; interacting with the capsid protein VP2, the viral double-stranded RNA (dsRNA) genome and the RNA-dependent RNA polymerase VP1. Here we investigate one of these VP3 functions and present the crystal structure of the ...[more]