Dataset Information
Differential impact of metabolic syndrome on subclinical atherosclerosis according to the presence of diabetes.
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ABSTRACT: Background
Metabolic syndrome (MS) is associated with increased risks of diabetes and atherosclerotic cardiovascular disease. However, data on the impact of MS and its individual components on subclinical atherosclerosis (SCA) according to diabetes status are scarce.Methods
Surrogate markers of SCA, brachial-ankle pulse wave velocity (baPWV), and carotid intima-medial thickness (IMT) and plaque were assessed in 2,560 subjects (60?±?8 years, 33% men) who participated in baseline health examinations for a community-based cohort study.Results
The participants included 2,149 non-diabetics (84%) and 411 diabetics (16%); 667 non-diabetics (31%) and 285 diabetics (69%) had MS, respectively. Diabetics had significantly higher baPWV and carotid IMT, and more plaques than non-diabetics (p?ConclusionsMS has an incremental impact on SCA in conditions without diabetes. The identification of MS and its individual components is more important for the risk stratification of CVD in non-diabetic individuals.
SUBMITTER: Won KB
PROVIDER: S-EPMC3599532 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Publications
Differential impact of metabolic syndrome on subclinical atherosclerosis according to the presence of diabetes.
Cardiovascular diabetology 20130304
<h4>Background</h4>Metabolic syndrome (MS) is associated with increased risks of diabetes and atherosclerotic cardiovascular disease. However, data on the impact of MS and its individual components on subclinical atherosclerosis (SCA) according to diabetes status are scarce.<h4>Methods</h4>Surrogate markers of SCA, brachial-ankle pulse wave velocity (baPWV), and carotid intima-medial thickness (IMT) and plaque were assessed in 2,560 subjects (60 ± 8 years, 33% men) who participated in baseline h ...[more]