The effects of fat mass and obesity-associated gene variants on the body mass index among ethnic groups and in children and adults.
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ABSTRACT:
SUBMITTER: Shinozaki K
PROVIDER: S-EPMC3602988 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
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The effects of fat mass and obesity-associated gene variants on the body mass index among ethnic groups and in children and adults.
Shinozaki Keiko K Okuda Masayuki M
Indian journal of endocrinology and metabolism 20121201 Suppl 3
Genome-wide association analyses have revealed common gene variations related to obesity. Variants of the fat mass and obesity-associated (FTO) gene among more than 40 genes studied were most closely associated with obesity, but the association varies among ethnicities. Moreover, the effect is significant in people of European descent as well as Asians, but less significant among people of African descent. Although the variants were also associated with type 2 diabetes and glucose homeostasis, t ...[more]
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