Ontology highlight
ABSTRACT:
SUBMITTER: Moller-Levet CS
PROVIDER: S-EPMC3607048 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Möller-Levet Carla S CS Archer Simon N SN Bucca Giselda G Laing Emma E EE Slak Ana A Kabiljo Renata R Lo June C Y JC Santhi Nayantara N von Schantz Malcolm M Smith Colin P CP Dijk Derk-Jan DJ
Proceedings of the National Academy of Sciences of the United States of America 20130225 12
Insufficient sleep and circadian rhythm disruption are associated with negative health outcomes, including obesity, cardiovascular disease, and cognitive impairment, but the mechanisms involved remain largely unexplored. Twenty-six participants were exposed to 1 wk of insufficient sleep (sleep-restriction condition 5.70 h, SEM = 0.03 sleep per 24 h) and 1 wk of sufficient sleep (control condition 8.50 h sleep, SEM = 0.11). Immediately following each condition, 10 whole-blood RNA samples were col ...[more]