Ontology highlight
ABSTRACT:
SUBMITTER: Wrzesinski SH
PROVIDER: S-EPMC3608935 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Wrzesinski Stephen H SH Fisher Jan L JL Ernstoff Marc S MS
Experimental hematology & oncology 20130309 1
Among the dendritic cell (DC) subsets, plasmacytoid DC's (pDC) are thought to be important in the generation of both antiviral and antitumor responses. While pDC may be useful in developing dendritic cell-based tumor vaccines, the low frequency of these cells in the peripheral blood has hampered attempts to understand their biology. To provide better insight into the biology of pDC, we isolated these unperturbed cells from the peripheral blood of healthy donors in order to further characterize t ...[more]