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Genomic analysis of ICEVchBan8: An atypical genetic element in Vibrio cholerae.

ABSTRACT: Genomic islands (GIs) and integrative conjugative elements (ICEs) are major players in bacterial evolution since they encode genes involved in adaptive functions of medical or environmental importance. Here we performed the genomic analysis of ICEVchBan8, an unusual ICE found in the genome of a clinical non-toxigenic Vibrio cholerae O37 isolate. ICEVchBan8 shares most of its genetic structure with SXT/R391 ICEs. However, this ICE codes for a different integration/excision module is located at a different insertion site, and part of its genetic cargo shows homology to other pathogenicity islands of V. cholerae.

SUBMITTER: Taviani E

PROVIDER: S-EPMC3612942 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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Genomic analysis of ICEVchBan8: An atypical genetic element in Vibrio cholerae.

Taviani Elisa E Spagnoletti Matteo M Ceccarelli Daniela D Haley Bradd J BJ Hasan Nur A NA Chen Arlene A Colombo Mauro M MM Huq Anwar A Colwell Rita R RR

FEBS letters 20120418 11

Genomic islands (GIs) and integrative conjugative elements (ICEs) are major players in bacterial evolution since they encode genes involved in adaptive functions of medical or environmental importance. Here we performed the genomic analysis of ICEVchBan8, an unusual ICE found in the genome of a clinical non-toxigenic Vibrio cholerae O37 isolate. ICEVchBan8 shares most of its genetic structure with SXT/R391 ICEs. However, this ICE codes for a different integration/excision module is located at a ...[more]

PMID: 22673571

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