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Rationality and emotionality: serotonin transporter genotype influences reasoning bias.

ABSTRACT: Reasoning often occurs under emotionally charged, opinion-laden circumstances. The belief-bias effect indexes the extent to which reasoning is based upon beliefs rather than logical structure. We examined whether emotional content increases this effect, particularly for adults genetically predisposed to be more emotionally reactive. SS/SL(G) carriers of the serotonin transporter genotype (5-HTTLPR) were less accurate selectively for evaluating emotional relational reasoning problems with belief-logic conflict relative to L(A)L(A) carriers. Trait anxiety was positively associated with emotional belief-bias, and the 5-HTTLPR genotype significantly accounted for the variance in this association. Thus, deductive reasoning, a higher cognitive ability, is sensitive to differences in emotionality rooted in serotonin neurotransmitter function.

SUBMITTER: Stollstorff M

PROVIDER: S-EPMC3624950 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature

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Rationality and emotionality: serotonin transporter genotype influences reasoning bias.

Stollstorff Melanie M Bean Stephanie E SE Anderson Lindsay M LM Devaney Joseph M JM Vaidya Chandan J CJ

Social cognitive and affective neuroscience 20120124 4

Reasoning often occurs under emotionally charged, opinion-laden circumstances. The belief-bias effect indexes the extent to which reasoning is based upon beliefs rather than logical structure. We examined whether emotional content increases this effect, particularly for adults genetically predisposed to be more emotionally reactive. SS/SL(G) carriers of the serotonin transporter genotype (5-HTTLPR) were less accurate selectively for evaluating emotional relational reasoning problems with belief- ...[more]

PMID: 22275169

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