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NHC-Cu-catalyzed protoboration of monosubstituted allenes. Ligand-controlled site selectivity, application to synthesis and mechanism.

ABSTRACT: Two types of NHC-Cu complexes catalyze protoborations of terminal allenes to afford valuable 1,1- or trisubstituted vinylboron species with high site selectivity and stereoselectivity. The scope of the method, application to natural product synthesis, and mechanistic basis for the observed selectivity trends are presented.

SUBMITTER: Meng F

PROVIDER: S-EPMC3625862 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature

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