Unknown

Dataset Information

0

Self-assembled magnetic bead biosensor for measuring bacterial growth and antimicrobial susceptibility testing.


ABSTRACT: Bacterial antibiotic resistance is one of the major concerns of modern healthcare worldwide, and the development of rapid, growth-based, antimicrobial susceptibility tests is key for addressing it. The cover image shows a self-assembled asynchronous magnetic bead rotation (AMBR) biosensor developed for rapid detection of bacterial growth. Using the biosensors, the minimum inhibitory concentration of a clinical E. coli isolate can be measured within two hours, where currently tests take 6-24 hours. A 16-well prototype is also constructed for simple and robust observation of the self-assembled AMBR biosensors.

SUBMITTER: Kinnunen P 

PROVIDER: S-EPMC3625966 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

altmetric image

Publications

Self-assembled magnetic bead biosensor for measuring bacterial growth and antimicrobial susceptibility testing.

Kinnunen Paivo P   McNaughton Brandon H BH   Albertson Theodore T   Sinn Irene I   Mofakham Sima S   Elbez Remy R   Newton Duane W DW   Hunt Alan A   Kopelman Raoul R  

Small (Weinheim an der Bergstrasse, Germany) 20120605 16


Bacterial antibiotic resistance is one of the major concerns of modern healthcare worldwide, and the development of rapid, growth-based, antimicrobial susceptibility tests is key for addressing it. The cover image shows a self-assembled asynchronous magnetic bead rotation (AMBR) biosensor developed for rapid detection of bacterial growth. Using the biosensors, the minimum inhibitory concentration of a clinical E. coli isolate can be measured within two hours, where currently tests take 6-24 hour  ...[more]

Similar Datasets

| S-EPMC4749332 | biostudies-literature
| S-EPMC8166823 | biostudies-literature
| S-EPMC2784131 | biostudies-literature
| PRJEB38234 | ENA
| S-EPMC8764967 | biostudies-literature
| S-EPMC3697729 | biostudies-literature
| S-EPMC8061348 | biostudies-literature
| S-EPMC4649152 | biostudies-other
| S-EPMC6329389 | biostudies-literature
| S-EPMC5690466 | biostudies-literature