Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Escobar B
PROVIDER: S-EPMC3629792 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Lopez-Escobar Beatriz B De Felipe Beatriz B Sanchez-Alcazar Jose Antonio JA Sasaki Takako T Copp Andrew J AJ Ybot-Gonzalez Patricia P
Developmental dynamics : an official publication of the American Association of Anatomists 20120904 11
<h4>Background</h4>The ventral ectodermal ridge (VER) is an important signalling centre in the mouse tail-bud following completion of gastrulation. BMP regulation is essential for VER function, but how these signals are transmitted between adjacent tissues is unclear.<h4>Results</h4>We investigated the idea that extracellular matrix components might be involved, using immunohistochemistry and in situ hybridisation to detect all known α, β, and γ laminin chains and their mRNAs in the early tail b ...[more]