Ontology highlight
ABSTRACT:
SUBMITTER: LaRock CN
PROVIDER: S-EPMC3631167 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
LaRock Christopher N CN Yu Jing J Horswill Alexander R AR Parsek Matthew R MR Minion F Chris FC
PloS one 20130419 4
The etiologic agent of bubonic plague, Yersinia pestis, senses self-produced, secreted chemical signals in a process named quorum sensing. Though the closely related enteric pathogen Y. pseudotuberculosis uses quorum sensing system to regulate motility, the role of quorum sensing in Y. pestis has been unclear. In this study we performed transcriptional profiling experiments to identify Y. pestis quorum sensing regulated functions. Our analysis revealed that acyl-homoserine lactone-based quorum s ...[more]