Ontology highlight
ABSTRACT:
SUBMITTER: Choi SH
PROVIDER: S-EPMC3659528 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Choi Sun-Hye SH Shin Tae-Joon TJ Hwang Sung-Hee SH Lee Byung-Hwan BH Kang Jiyeon J Kim Hyeon-Joong HJ Oh Jae-Wook JW Bae Chun Sik CS Lee Soo-Han SH Nah Seung-Yeol SY
Journal of ginseng research 20110601 2
The human ether-a-go-go-related gene (HERG) cardiac K(+) channels are one of the representative pharmacological targets for development of drugs against cardiovascular diseases such as arrhythmia. Panax ginseng has been known to exhibit cardioprotective effects. In a previous report we demonstrated that ginsenoside Rg3 regulates HERG K(+) channels by decelerating deactivation. However, little is known about how ginsenoside metabolites regulate HERG K(+) channel activity. In the present study, we ...[more]