Ontology highlight
ABSTRACT:
SUBMITTER: Lo Vasco VR
PROVIDER: S-EPMC3660692 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Lo Vasco Vincenza Rita VR Leopizzi Martina M Chiappetta Caterina C Puggioni Chiara C Di Cristofano Claudio C Della Rocca Carlo C
Journal of cell communication and signaling 20130222 2
The definition of the number and nature of signal transduction pathways networking in the pathogenesis of osteosarcoma raised great interest. Intracellular calcium ions are important second messengers implicated in the control of cell death. The calcium concentration is regulated by signal transduction pathways, including the Phosphoinositides (PI) signaling. Phosphatydil inositol (4,5) bisphosphate (PIP2) is critical for many cellular activities. The levels of PIP2 are regulated by means of Pho ...[more]