Ontology highlight
ABSTRACT:
SUBMITTER: Zhou V
PROVIDER: S-EPMC3665722 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Zhou Vivian V Yassai Maryam B MB Regunathan Jeyarani J Box Jodie J Bosenko Dmitry D Vashishath Yashu Y Demos Wendy W Lee Fong F Gorski Jack J
Human immunology 20130104 7
The CD8 memory T cell repertoire to the influenza A derived M1(58-66) epitope shows a restricted V genes and CDR3 sequences usage. The repertoire is highly polyclonal and the clonotype distribution has been described as consisting of two components, one showing a power law-like distribution and the other composed of a few clonotypes with a very high relative frequency. The question is whether the complex repertoire defined by its ability to flourish in a short term recall culture corresponded to ...[more]