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ABSTRACT:
SUBMITTER: Kudryashov DS
PROVIDER: S-EPMC3670783 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Biopolymers 20130401 4
This minireview is dedicated to the memory of Henryk Eisenberg and honors his major contributions to many areas of biophysics and to the analysis of macromolecular states and interactions in particular. This work reviews the ATP and ADP states of a ubiquitous protein, actins, and considers the present evidence for and against unique, nucleotide-dependent conformations of this protein. The effects of ATP and ADP on specific structural elements of actins, its loops and clefts, as revealed by mutat ...[more]