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Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar.


ABSTRACT: Treponema pallidum resistance to azithromycin has been documented in the US, Canada, and Ireland. We found no evidence of resistance to azithromycin in specimens from 141 patients with syphilitic lesions in Madagascar suggesting resistance is geographically isolated and supporting use of azithromycin as alternative treatment for early syphilis in Madagascar.

SUBMITTER: Van Damme K 

PROVIDER: S-EPMC3673283 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar.

Van Damme Kathleen K   Behets Frieda F   Ravelomanana Noro N   Godornes Charmie C   Khan Maria M   Randrianasolo Bodo B   Rabenja Ny Lovaniaina NL   Lukehart Sheila S   Cohen Myron M   Hook Edward E  

Sexually transmitted diseases 20091201 12


Treponema pallidum resistance to azithromycin has been documented in the US, Canada, and Ireland. We found no evidence of resistance to azithromycin in specimens from 141 patients with syphilitic lesions in Madagascar suggesting resistance is geographically isolated and supporting use of azithromycin as alternative treatment for early syphilis in Madagascar. ...[more]

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