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6'-(1,3-Diphenyl-1H-pyrazol-4-yl)-7'-(1H-indol-3-ylcarbon-yl)-2-oxo-1-(prop-2-en-1-yl)-5',6',7',7a'-tetra-hydro-1'H-spiro-[indoline-3,5'-pyrrolo-[1,2-c][1,3]thia-zole]-7'-carbo-nitrile.

ABSTRACT: In the title compound, C41H32N6O2S, the pyrrolo-thia-zole ring system is folded about the bridging N-C bond. The thia-zolidine and pyrrolidine rings adopt envelope (with the fused C atom as the flap) and twisted conformations, respectively. The two phenyl rings attached to the pyrazole ring are twisted from the plane of the latter by 6.8 (1) and 52.8 (1)°. The allyl group is disordered over two conformations in a 0.805 (6):0.195 (6) ratio. In the crystal, pairs of N-H⋯O hydrogen bonds link the mol-ecules into centrosymmetric dimers.

SUBMITTER: Kannan PS

PROVIDER: S-EPMC3684939 | biostudies-literature |

REPOSITORIES: biostudies-literature

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