Ontology highlight
ABSTRACT:
SUBMITTER: Thompson HM
PROVIDER: S-EPMC3690653 | biostudies-literature | 2002 Dec
REPOSITORIES: biostudies-literature
Thompson Heather M HM Skop Ahna R AR Euteneuer Ursula U Meyer Barbara J BJ McNiven Mark A MA
Current biology : CB 20021201 24
Cytokinesis involves the concerted efforts of the microtubule and actin cytoskeletons as well as vesicle trafficking and membrane remodeling to form the cleavage furrow and complete daughter cell separation. The exact mechanisms that support membrane remodeling during cytokinesis remain largely undefined. In this study, we report that the large GTPase dynamin, a protein involved in membrane tubulation and vesiculation, is essential for successful cytokinesis. Using biochemical and morphological ...[more]