Ontology highlight
ABSTRACT:
SUBMITTER: Joseph AP
PROVIDER: S-EPMC7254831 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Joseph Agnel Praveen AP Lagerstedt Ingvar I Jakobi Arjen A Burnley Tom T Patwardhan Ardan A Topf Maya M Winn Martyn M
Journal of chemical information and modeling 20200211 5
Cryogenic electron microscopy (cryo-EM) is a powerful technique for determining structures of multiple conformational or compositional states of macromolecular assemblies involved in cellular processes. Recent technological developments have led to a leap in the resolution of many cryo-EM data sets, making atomic model building more common for data interpretation. We present a method for calculating differences between two cryo-EM maps or a map and a fitted atomic model. The proposed approach wo ...[more]