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High-throughput sequencing of cytosine methylation in plant DNA.


ABSTRACT: : Cytosine methylation is a significant and widespread regulatory factor in plant systems. Methods for the high-throughput sequencing of methylation have allowed a greatly improved characterisation of the methylome. Here we discuss currently available methods for generation and analysis of high-throughput sequencing of methylation data. We also discuss the results previously acquired through sequencing plant methylomes, and highlight remaining challenges in this field.

SUBMITTER: Hardcastle TJ 

PROVIDER: S-EPMC3691832 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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High-throughput sequencing of cytosine methylation in plant DNA.

Hardcastle Thomas J TJ  

Plant methods 20130607 1


: Cytosine methylation is a significant and widespread regulatory factor in plant systems. Methods for the high-throughput sequencing of methylation have allowed a greatly improved characterisation of the methylome. Here we discuss currently available methods for generation and analysis of high-throughput sequencing of methylation data. We also discuss the results previously acquired through sequencing plant methylomes, and highlight remaining challenges in this field. ...[more]

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