Ontology highlight
ABSTRACT:
SUBMITTER: Evdokimov A
PROVIDER: S-EPMC3695498 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Evdokimov Alexey A Petruseva Irina I Tsidulko Aleksandra A Koroleva Ludmila L Serpokrylova Inna I Silnikov Vladimir V Lavrik Olga O
Nucleic acids research 20130422 12
DNA probes for the studies of damaged strand excision during the nucleotide excision repair (NER) have been designed using the novel non-nucleosidic phosphoramidite reagents that contain N-[6-(9-antracenylcarbamoyl)hexanoyl]-3-amino-1,2-propandiol (nAnt) and N-[6-(5(6)-fluoresceinylcarbamoyl)hexanoyl]-3-amino-1,2-propandiol (nFlu) moieties. New lesion-imitating adducts being inserted into DNA show good substrate properties in NER process. Modified extended linear nFlu- and nAntr-DNA are suitable ...[more]