Ontology highlight
ABSTRACT:
SUBMITTER: Miao Z
PROVIDER: S-EPMC3704159 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Miao Zhixin Z Wu Shiyong S Chen Hao H
Journal of the American Society for Mass Spectrometry 20100611 10
The direct sampling feature of liquid sample desorption electrospray ionization (DESI) allows the ionization of liquid samples without adding acids/organic solvents (i.e., without sample pretreatment). As a result, it provides a new approach for probing protein conformation in solution. In this study, it has been observed that native protein ions are generated from proteins in water by DESI. Interestingly, the intensities of the resulting protein ions appear to be higher than those generated by ...[more]