Ontology highlight
ABSTRACT:
SUBMITTER: Pathai S
PROVIDER: S-EPMC3710972 | biostudies-literature | 2013 Jul-Aug
REPOSITORIES: biostudies-literature
Pathai Sophia S Gilbert Clare E CE Lawn Stephen D SD Weiss Helen A HA Peto Tunde T Cook Colin C Wong Tien Y TY Shiels Paul G PG
Mechanisms of ageing and development 20130520 7-8
Certain anatomic and functional parameters of the eye change with increasing chronological age. They may, therefore, serve as potential biomarkers of ageing. We investigated associations between four such ocular parameters (lens density, retinal vessel calibre, corneal endothelial cells and retinal nerve fibre layer thickness) and two 'cellular' biomarkers of ageing (leukocyte telomere length and CDKN2A expression), with frailty (a clinical correlate of biological ageing) in a population of Sout ...[more]