Ontology highlight
ABSTRACT:
SUBMITTER: Mason C
PROVIDER: S-EPMC3732802 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Mason Caitlin C Xiao Liren L Duggan Catherine C Imayama Ikuyo I Foster-Schubert Karen E KE Kong Angela A Campbell Kristin L KL Wang Ching-Yun CY Alfano Catherine M CM Blackburn George L GL Pollack Michael M McTiernan Anne A
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20130611 8
High levels of insulin-like growth factor (IGF)-I may increase the risk of common cancers in humans. We hypothesized that weight loss induced by diet and/or exercise would reduce IGF-I in postmenopausal women. Four hundred and thirty nine overweight or obese [body mass index (BMI) ≥ 25 kg/m(2)] women (50-75 years) were randomly assigned to: (i) exercise (N = 117), (ii) dietary weight loss (N = 118), (iii) diet + exercise (N = 117), or (iv) control (N = 87). The diet intervention was a group-base ...[more]