A dancer caught midstep: the structure of ATP-bound Hsp70.
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ABSTRACT:
SUBMITTER: Sousa R
PROVIDER: S-EPMC3746503 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
Publications
Hsp70 ATP binding induces substrate release, but the transiency of this state has inhibited its characterization. In this issue, Kityk et al. determine the Hsp70(∗)ATP structure utilizing engineered disulfide bonds, providing insights into the workings of this essential molecular machine. ...[more]
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