Ontology highlight
ABSTRACT:
SUBMITTER: Murta D
PROVIDER: S-EPMC3755970 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PloS one 20130828 8
The transcription and expression patterns of Notch pathway components (Notch 1-3, Delta1 and 4, Jagged1) and effectors (Hes1, Hes2, Hes5 and Nrarp) were evaluated (through RT-PCR and IHC) in the mouse testis at key moments of post-natal development, and along the adult spermatogenic cycle. Notch pathway components and effectors are transcribed in the testis and expressed in germ, Sertoli and Leydig cells, and each Notch component shows a specific cell-type and time-window expression pattern. Thi ...[more]