Ontology highlight
ABSTRACT:
SUBMITTER: Picard N
PROVIDER: S-EPMC3757119 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Picard Nathalie N Matsuzaka Yoshiya Y Strick Peter L PL
Nature neuroscience 20130804 9
How does long-term training and the development of motor skills modify the activity of the primary motor cortex (M1)? To address this issue, we trained monkeys for ~1-6 years to perform visually guided and internally generated sequences of reaching movements. Then, we used [(14)C]2-deoxyglucose (2DG) uptake and single-neuron recording to measure metabolic and neuron activity in M1. After extended practice, we observed a profound reduction of metabolic activity in M1 for the performance of intern ...[more]