Ontology highlight
ABSTRACT:
SUBMITTER: Denoeud F
PROVIDER: S-EPMC3760481 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Denoeud France F Henriet Simon S Mungpakdee Sutada S Aury Jean-Marc JM Da Silva Corinne C Brinkmann Henner H Mikhaleva Jana J Olsen Lisbeth Charlotte LC Jubin Claire C Cañestro Cristian C Bouquet Jean-Marie JM Danks Gemma G Poulain Julie J Campsteijn Coen C Adamski Marcin M Cross Ismael I Yadetie Fekadu F Muffato Matthieu M Louis Alexandra A Butcher Stephen S Tsagkogeorga Georgia G Konrad Anke A Singh Sarabdeep S Jensen Marit Flo MF Huynh Cong Evelyne E Eikeseth-Otteraa Helen H Noel Benjamin B Anthouard Véronique V Porcel Betina M BM Kachouri-Lafond Rym R Nishino Atsuo A Ugolini Matteo M Chourrout Pascal P Nishida Hiroki H Aasland Rein R Huzurbazar Snehalata S Westhof Eric E Delsuc Frédéric F Lehrach Hans H Reinhardt Richard R Weissenbach Jean J Roy Scott W SW Artiguenave François F Postlethwait John H JH Manak J Robert JR Thompson Eric M EM Jaillon Olivier O Du Pasquier Louis L Boudinot Pierre P Liberles David A DA Volff Jean-Nicolas JN Philippe Hervé H Lenhard Boris B Roest Crollius Hugues H Wincker Patrick P Chourrout Daniel D
Science (New York, N.Y.) 20101118 6009
Genomes of animals as different as sponges and humans show conservation of global architecture. Here we show that multiple genomic features including transposon diversity, developmental gene repertoire, physical gene order, and intron-exon organization are shattered in the tunicate Oikopleura, belonging to the sister group of vertebrates and retaining chordate morphology. Ancestral architecture of animal genomes can be deeply modified and may therefore be largely nonadaptive. This rapidly evolvi ...[more]