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Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids.


ABSTRACT: A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions.

SUBMITTER: DeBergh JR 

PROVIDER: S-EPMC3766840 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Synthesis of aryl sulfonamides via palladium-catalyzed chlorosulfonylation of arylboronic acids.

DeBergh J Robb JR   Niljianskul Nootaree N   Buchwald Stephen L SL  

Journal of the American Chemical Society 20130712 29


A palladium-catalyzed method for the preparation of sulfonamides is described. The process exhibits significant functional group tolerance and allows for the preparation of a number of arylsulfonyl chlorides and sulfonamides under mild conditions. ...[more]

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