Ontology highlight
ABSTRACT:
SUBMITTER: Singh S
PROVIDER: S-EPMC3769852 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] 20110401 2
Haemorrhagic Septicaemia (HS), an acute and fatal disease of cattle and buffalo is primarily caused by serotype B:2 or E:2 of Pasteurella multocida. The transferrin binding protein A (TbpA) has been found to act as immunogen and potent vaccine candidate in various Gram negative bacteria including P. multocida. The present study was carried out to evaluate the potential of this antigen as a DNA vaccine against HS in mice model. The tbpA gene of P. multocida serotype B:2 was cloned in a mammalian ...[more]