Ontology highlight
ABSTRACT:
SUBMITTER: Suzuki A
PROVIDER: S-EPMC3772023 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Suzuki Ayako A Mimaki Sachiyo S Yamane Yuki Y Kawase Akikazu A Matsushima Koutatsu K Suzuki Makito M Goto Koichi K Sugano Sumio S Esumi Hiroyasu H Suzuki Yutaka Y Tsuchihara Katsuya K
PloS one 20130912 9
We analyzed whole-exome sequencing data from 97 Japanese lung adenocarcinoma patients and identified several putative cancer-related genes and pathways. Particularly, we observed that cancer-related mutation patterns were significantly different between different ethnic groups. As previously reported, mutations in the EGFR gene were characteristic to Japanese, while those in the KRAS gene were more frequent in Caucasians. Furthermore, during the course of this analysis, we found that cancer-spec ...[more]