Ontology highlight
ABSTRACT:
SUBMITTER: Jeziorski MC
PROVIDER: S-EPMC3788357 | biostudies-literature | 2006 May
REPOSITORIES: biostudies-literature
Jeziorski Michael C MC Greenberg Robert M RM
International journal for parasitology 20060307 6
Voltage-gated calcium (Ca2+) channels provide the pathway for Ca2+ influxes that underlie Ca2+ -dependent responses in muscles, nerves and other excitable cells. They are also targets of a wide variety of drugs and toxins. Ca2+ channels are multisubunit protein complexes consisting of a pore-forming alpha(1) subunit and other modulatory subunits, including the beta subunit. Here, we review the structure and function of schistosome Ca2+ channel subunits, with particular emphasis on variant Ca2+ c ...[more]