Ontology highlight
ABSTRACT:
SUBMITTER: Lewis BB
PROVIDER: S-EPMC6697093 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Lewis Brittany B BB Wester Matthew R MR Miller Lauren E LE Nagarkar Maitreyi D MD Johnson M Brittany MB Saha Margaret S MS
Developmental dynamics : an official publication of the American Association of Anatomists 20091101 11
Voltage-gated calcium channels play a critical role in regulating the Ca2+ activity that mediates many aspects of neural development, including neural induction, neurotransmitter phenotype specification, and neurite outgrowth. Using Xenopus laevis embryos, we describe the spatial and temporal expression patterns during development of the 10 pore-forming alpha1 subunits that define the channels' kinetic properties. In situ hybridization indicates that CaV1.2, CaV2.1, CaV2.2, and CaV3.2 are expres ...[more]