Ontology highlight
ABSTRACT:
SUBMITTER: Heymann JB
PROVIDER: S-EPMC3796050 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Heymann J Bernard JB Winkler Dennis C DC Yim Yang-In YI Eisenberg Evan E Greene Lois E LE Steven Alasdair C AC
Journal of structural biology 20130518 1
Clathrin coats, which stabilize membrane curvature during endocytosis and vesicular trafficking, form highly polymorphic fullerene lattices. We used cryo-electron tomography to visualize coated particles in isolates from bovine brain. The particles range from ∼66 to ∼134nm in diameter, and only 20% of them (all ⩾80nm) contain vesicles. The remaining 80% are clathrin "baskets", presumably artifactual assembly products. Polyhedral models were built for 54 distinct coat geometries. In true coated v ...[more]