Ontology highlight
ABSTRACT:
SUBMITTER: Tang Q
PROVIDER: S-EPMC3808774 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Cold Spring Harbor perspectives in medicine 20131101 11
Regulatory T cells (Tregs) are essential to transplantation tolerance and their therapeutic efficacy is well documented in animal models. Moreover, human Tregs can be identified, isolated, and expanded in short-term ex vivo cultures so that a therapeutic product can be manufactured at relevant doses. Treg therapy is being planned at multiple transplant centers around the world. In this article, we review topics critical to effective implementation of Treg therapy in transplantation. We will addr ...[more]