Ontology highlight
ABSTRACT:
SUBMITTER: Cheung TH
PROVIDER: S-EPMC3808888 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Cheung Tom H TH Rando Thomas A TA
Nature reviews. Molecular cell biology 20130601 6
Subsets of mammalian adult stem cells reside in the quiescent state for prolonged periods of time. This state, which is reversible, has long been viewed as dormant and with minimal basal activity. Recent advances in adult stem cell isolation have provided insights into the epigenetic, transcriptional and post-transcriptional control of quiescence and suggest that quiescence is an actively maintained state in which signalling pathways are involved in maintaining a poised state that allows rapid a ...[more]